React4life Updates

Organized by the European Association for Cancer Research, the conference brings together experts investigating cancer biology through next-generation 3D and in vivo models, advancing understanding of tumor mechanics, cellular interactions, and molecular regulation of cancer progression.

B2B, an EU-funded project coordinated by Silvia Scaglione (CNR and React4Life), has successfully developed a pioneering 3D organ-on-chip model of spontaneous breast cancer metastasis to bone. This innovative Breast-to-Bone (B2B) device recreates physiological interactions between cancer and bone tissues, advancing research and accelerating drug discovery against metastatic breast cancer

The MPS World Summit returns for its second edition in Berlin, uniting scientists and stakeholders from around the world to explore advances in organ-on-chip and human-relevant models, driving forward innovation in biomedical and regulatory science.

The 2023 TERMIS EU Conference in Manchester brings together researchers, clinicians, and industry experts to share cutting-edge advances in tissue engineering and regenerative medicine

MIVO® enables the real-time study of immune–tumor interactions under physiologically relevant flow. This organ-on-chip platform captures NK cell migration, extravasation, and cytotoxic activity against 3D tumors, while revealing mechanisms of immune resistance—offering a powerful, human-relevant model for advancing immuno-oncology research and therapeutic development.

GlycoNoVi, a Horizon Europe Marie Skłodowska-Curie Actions Doctoral Network coordinated by the University of Florence, brings together leading academic and industrial partners to unravel the molecular mechanisms of Norovirus infection. As industrial leader, React4Life will apply its MIVO® organ-on-chip technology to model human intestinal responses and accelerate antiviral drug discovery.

MIVO-HTS platform is a multi-organ-on-chip emulating organs of the human body in the lab and it is based on MIVO® Technology.
It will improve and accelerate drug testing in the preclinical phase, discover novel personalized therapies and reduce animal testing.

The Italian Society of Organ-on-Chip (SIOoC) unites leading academic and industrial experts to advance organ-on-chip research. React4life, among the founding members, supports this milestone initiative fostering innovation and collaboration across disciplines.

Silvia Scaglione, co-founder at React4life, presented MIVO, the patented organ-on-chip platform that mimics human physiology, enabling efficient drug testing in cancer, immunotherapy, and cardiac research, recognized at the 20th Italian L’Oréal–UNESCO Women in Science Award.

React4Life publishes a new study showcasing a dynamic 3D ovarian cancer model within the MIVO® platform. By mimicking systemic drug perfusion, the model accurately predicts in vivo responses in just one week—accelerating efficacy testing and reducing animal use in cancer drug development