News and events2020-10-28T17:28:40+00:00

React4life in the global news

The challenge of the cosmetics industry: discovering compounds that block pollutants in contact with the skin.

Scientific research shows that polluting particles are extremely fine and highly dangerous. Our test allows to quantify the percentage of particulate passes through the skin model to determine the protective factor of the cosmetic compound. We call it "antipollution test": it is fast, innovative and effective. Air pollution can cause serious health problems, especially when the exposure to certain pollutants occurs for a prolonged period of time. According to the World Health Organization, the concentration of pollutants in the air significantly exceeds the recommended limits, and it is the cause of millions of deaths worldwide - /en/, while [...]

November 18th, 2020|

Reducing the time and cost of screening for new compounds and limiting the number of animals used in in-vivo tests is the future of drug discovery.

Cristina Degrassi, CEO of MTTLab, tells us about her experience with React4life which led to the publication of the paper on Altex: "3D fluid-dynamic ovarian cancer model resembling systemic drug administration for efficacy assay". The ability to control drugs quickly and efficiently with a more accurate preclinical tumor model is of great importance in drug development, as the tests used still have severe problems and poor predictivity. Considering the limitations of animal experiments to predict human response and the high need for new drugs, it is necessary to include highly reproducible human systemic tumor models in preclinical analyzes to [...]

October 16th, 2020|

MIVO® and intestinal permeability, a perfect combination to study the absorption mechanism and the biological effects of drugs and food compounds

MIVO®  technology has made possible the implementation of a fluidic 3D in vitro model of the intestinal barrier. In this article it is demonstrated that MIVO®, combined with a 3D intestinal epithelium model, allows to emulate the intestinal environment in vitro, as a reliable platform for the study of the passage of molecules, discriminating the two main intestinal absorption mechanisms. This platform therefore can be employed for the quantification of the absorption of oral drugs. The intestinal epithelium has a well-organized cellular structure, with different cellular phenotypes and barrier properties that make it effective against the excessive absorption of [...]

August 27th, 2020|

Livia, React4lifer to learn the techniques of an R&D laboratory

Polyglot, bioengineer, pianist and a few weeks ago React4lifer! We introduce Livia who is doing a stage in our R&D district in Vimodrone Livia, tell us about yourself I am an Italian girl, born and raised in Brussels and I am currently studying Biomedical Engineering at Imperial College London. Overall, I am a creative person, I enjoy drawing and playing the piano. In addition, I am involved in multiple student-led projects and activities. Last year, I was the Bioengineering Society’s Wellbeing Events Officer and the Israel Tech Society’s Fundraising Officer. Working in teams to achieve measurable and beneficial goals [...]

August 6th, 2020|

3D Human Cancer Models with MIVO and Culturing 3D Tissues: we talk about it today at the Drug Discovery summit

"A Biology-Driven Multi-Chamber Device For Culturing 3D Tissues And Performing Reliable Absorption Assays" and "3D Human Cancer Models Within The MIVO- Multi In Vitro Organ Fluidic Device For Improving The Outcome Of In Vitro Drug Testing" are the titles of our poster on Oxofrod Global today. We are proud to be here to present our Organ on chip technology for the discovery of drugs in new ways in the discovery of biotherapies, proteins, cells and genetic bases. The purpose of this event is to present the pharma world and discover the latest updates on the integration of screening approaches [...]

July 30th, 2020|

Covid19 and heart: an advanced in vitro research on infection mechanism

Monzino and Spallanzani, with the biotech React4life, join forces to study new therapies to protect the heart from the virus. Regione Lombardia finances the Cardio-Cov research project. To understand the mechanisms on the heart connected to COVID-19, Centro Cardiologico Monzino, with the collaboration of the National Institute of Infectious Diseases (INMI) "Lazzaro Spallanzani" in Rome and the innovative biomedical research company React4life, has obteined from Regione Lombardy a € 513,000 in funding for a six-monthly research project entitled "Effects of COVID-19 infection on inflammation and cardiac fibrosis. In vitro modeling: Cardio-Cov ". Since the beginning of the pandemic, the [...]

July 16th, 2020|

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