MIVO® – Webinar
14th May 20253:00 PM – CET
Niosomes and Peptide Nanofibers as Delivery Platforms to Boost Anti-Tumor Immunity
Over the past two decades, Tumor-Associated Carbohydrate Antigens (TACAs) have emerged as promising targets for cancer vaccine development.
Among them, the Tn antigen is particularly interesting because it is hidden on healthy cells but exposed on cancer cells—making it an ideal immunotherapy target. However, triggering a strong and lasting immune response against Tn remains a challenge. In this webinar, we will present a stable and immunogenic Tn antigen mimetic, specifically designed to enhance the body’s latent response against cancer.
We will explore two delivery strategies—niosomes and self-assembling peptide nanofibers—that enable precise and effective presentation of the mimetic to the immune system. Their efficacy was finally tested by using the cancer on chip platform
INFO
About the speakers
ABOUT THE SPEAKER
Dr. Cristina Nativi is a Full Professor of Organic Chemistry at the University of Florence, where she has been a faculty member since 1991. Her academic journey includes postdoctoral research supported by a NATO grant at the Université de Montréal (Canada), where she developed O- and C-glycosylation methods under the supervision of Prof. S. Hanessian, and a Swiss Government Fellowship at the Université de Lausanne (Switzerland), working on the total synthesis of saccharides from “naked sugars” with Prof. P. Vogel. She earned her degree in Chemistry summa cum laude from the University of Florence, focusing on stereoselective synthesis mediated by tin, under the supervision of Prof. A. Ricci and Prof. M. Taddei.
Prof. Nativi is the author of over 190 scientific publications, 5 book chapters, and holds 5 licensed patents. She is actively involved in technology transfer and has led numerous national and European research projects as Principal Investigator. In recognition of her contributions to the Life Sciences, she was awarded the Organic Division Prize of the Italian Chemical Society (SCI) in 2019, and was featured in the ACS Omega 2020 collection “Women at the Forefront of Chemistry.”
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