Our MIVO® – Webinar

Join our webinar about our innovative MIVO® technology

Fluid-dynamic multi-in vitro organ (MIVO®) applications for cancer cell plasticity

When: March 30th, 2:30 pm CET / 8:30 am EST.
Register here: https://us02web.zoom.us/webinar/register/WN_vXdBDL4bTSGLlz-zSGqO7w

One of the main issues in biological and medical research is the need of reliable tools for physiologically relevant human modeling. This is particularly true for cancer research, since drug resistance and cancer-related deaths still represent a major challenge. The MIVO technology encloses a fluidic multi-chamber platform that can easily adapt to multiple applications, from the basic biological characterization/targets identification to pharmacological testing, in a humanized in vitro model. MIVO is perfectly customizable, so that the researcher can recapitulate the desired micro-physiological/micropathological system in a well, in order to improve and speed-up basic and pharmacological research.

Cancer stem cells (CSCs) are considered the root of the primary and the metastatic tumor mass, and responsible of drug resistance. Thus, the understanding of CSCs biology represents the basis for the improvement of cancer therapies.

This webinar wants to shed a spotlight on the possible application of the MIVO device in the field of cancer stem cells/cancer cell plasticity: the possibility to shape a reliable cancer model could provide a powerful tool for the study the CSC biology and the pharmacological screening of anticancer drugs.

About the speaker: Dr. Monica Marzagalli Senior Cell Biology Scientist at React4life and Adjunct Professor (Laboratory of General and Cellular Biology), University of Milano

Monica graduated in Drug Biotechnology at the University of Milano, Italy, where she later obtained her PhD in Endocrinological and Metabolic Sciences, in 2015. Since the beginning of her career, her research focused on tumor biology, with emphasis on the cellular and molecular mechanisms of melanoma progression, on its pharmacological targeting and on the characterization of the cancer stem cell-subpopulation. Given her growing interest in the tumor immune microenvironment, in 2017 she flew to Los Angeles, where she worked as a Postdoc at City of Hope National Medical Center, acquiring immunooncology-related skills. Moving back to the University of Milano, she started working on the cross-talk between cancer stem cells and tumor-associated neutrophils, finally landing to React4life as a Senior Cell Biology Scientist.

3D TISSUE MODELS FOR PRECLINICAL IN VITRO ASSAYS

When: February 18th, 3:30 pm CET / 9:30 am EST.
Register here: https://bit.ly/3qzw4Ms

Do you want to learn more about establishing robust #3Dcellculture models? Subscribe this webinar in collaboration with Obatala Sciences!

About the speakers:
Silvia Scaglione is a biomedical engineering, CSO, head of R&d team and co-founder of React4life.
She is currently author of more than 60 peer-reviewed papers on international journals and inventor on 7 patent applications.
She is also coordinator of a H2020-Future Emerging Technology (FET-OPEN) project about a spontaneous breast-to-bone in vitro metastasis model B2B From breast to bone

Trivia Frazier, PhD, MBA is a native of New Orleans and an experienced Adult Stem Cell Researcher and Biotech Business Professional with 15+ years of experience in basic science research, and management. She holds bachelor’s degrees in Physics and Biomedical Engineering, an MBA with a concentration in Finance, and a PhD in Biomedical Sciences. She completed her postdoctoral training at Pennington Biomedical Research Center and the Tulane Center for Stem Research and Regenerative Medicine. She has trained and collaborated with national and international key opinion leaders and worked with clinicians within the areas of Tissue Engineering and Regenerative Medicine, Breast and Bone Oncology, Obesity, Stem Cell Transplantation, and Diabetes.

FLUID-DYNAMIC MULTI-IN-VITRO ORGAN MIVO BASED ASSAYS FOR IN VITRO DRUG TESTING

When: Jan 21th, 3 pm CET / 9 am EST.
Register here: https://lnkd.in/ex9TyW6

The development of new molecules and innovative therapies is often hampered by unreliable, poor standardized and time-consuming disease models.
During this webinar, Silvia Scaglione, Chief Scientist Officer of #React4life will discuss how MIVO® is a valuable tool for in vitro drug testing. You will learn:
– how MIVO® can be used to culture 3D cancer models and testing the efficacy of drugs;
– how MIVO® supports the culture of 3D cancer models and flowing immune cells to study their cross-talk and test immunotherapies.