A novel organ-on-chip-based in vitro approach for co-culturing 3D human cancer tissues & circulating capillary flow-driven immune cells for more predictive drug testing & human disease modeling
A novel 3D, fully humanized in vitro cancer tissue model has been recently optimized by combining emerging technologies such as organ on a chip platforms and 3D cell laden hydrogels. In particular, a novel Multi-In Vitro
Organ (MIVO®) device has been recently adopted to culture 3D clinically relevant size cancer tissues under proper physiological culture conditions to investigate the efficacy of anticancer treatments.
- Conference:
- Authors: Silvia Scaglione1,2, M. Marzagalli 1, C. Vitale3, R. Castriconi3, C. Bottino4, M. Aiello1,2
1 National Research Council (CNR) – Italy
2 React4life, Genoa – Italy
3 DIMES, Univ. Genoa – Italy
4 Gaslini Hospital, Genoa – Italy
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