A human relevant multi-organ & multi-fluidic Gut-BBB-on-chip to model gut-brain axis in vitro

Communication between the gut and the brain is increasingly recognized as a key regulator of disease. Still, models that replicate this interaction in a dynamic and human-relevant way are missing.
To overcome this limitation a multiorgan gut-brain axis model was developed using the MIVO Organ on chip platform, fluidically coupling a double-flow gut model to a downstream BBB module.

- - - - Conference: MPS 2026, Washington
      - Authors: Elisa Raboni^1,2, Elisabetta Palamà¹, Maurizio Aiello^2,3, Marco Fato¹, Silvia Scaglione^2,3

¹University of Genova, Genoa (Italy)
²React4life, Genoa (Italy)
³Consiglio Nazionale delle Ricerche (CNR)

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A human relevant multi-organ & multi-fluidic Gut-BBB-on-chip to model gut-brain axis in vitro

Fill the form below to get your copy

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