A Dynamic Double-Flow Gut-on-Chip Model for Predictive Absorption Studies In Vitro

This study aims to overcome the limitations of traditional in vitro and animal models by developing a novel gut-on-chip system, which integrates CaCo-2/HT-29 co-cultures in a dynamic environment.
The model accelerates cell maturation, enhances barrier function, and offers a more accurate platform for drug testing, disease modeling, and toxicity assessment.

- - Conference: MPS World Summit 2025, Brusselles
  - Authors:Gergő Borka¹, E. Palamà¹, M. Aiello^1,2, S. Scaglione^1,2

¹React4life, Genoa (Italy)
²National Research Council (CNR)

A Dynamic Double-Flow Gut-on-Chip Model for Predictive Absorption Studies In Vitro

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A Dynamic Double-Flow Gut-on-Chip Model for Predictive Absorption Studies In Vitro

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