MIVO technology allows the hosting and culture of 2D-3D cellularized intestinal models (e.g. CaCo2 cells monolayer, EpiIntestinal tissues) under fluid-dynamic conditions.
This assay allows to analyse the absorption of compounds at intestinal levels and measure over time the percentage of an intestine permeation. It is easy to create new opportunities for yourself in the agri-food sector with our bioreactor offerings.
In this recent paper (Marrella et al. 2020 ALtex) the team of React4life showed that intestinal permeation results observed in vitro within MIVO device were in line with those obtained in vivo, validating this approach as a reliable platform for mimicking the intestinal epithelium for in vitro nutraceuticals permeation tests.