Our innovative patented method that allows the in vitro quantification of the percentage of particulate penetrating the skin and the protection offered by cosmetic compound.
The fluidic device MIVO® (Multi In Vitro Organ) is able to host several human skin tissues (cellular monolayers,reconstituted 3D tissues) and to mimic the living environment of epithelial tissues. The percentage of the pollutant detected on the skin’s surface, in the donor and the receiver chamber is calculated for the treated and control samples.
The protection pollutant factor of cosmetic ingredient is then derived.
The patented method provides to detect and measure the percentage of urban particulate passed through the tissue layer, compared to the control of untreated skin with the anti-pollution lotion to be tested.
The MIVO® device has been successfully used to conduct antipollution tests; MIVO chamber is loaded with pollution solution, properly chosen to recapitulate the urban dust and both chemical and biological outcomes are measured within the same test.