Growing 2D cell cultures outside their natural system in an artificially created microenvironment has been the gold standard for decades. These models were used to setup predictable and reproducible in-vitro models to test scientists’ experimental hypothesis, mostly due to their ease of use and low cost.
However, real tissues are made of cells in a 3D conformation, and everything that happens to any given cell is not just a result of a 2D exchange, but of a multitude of interactions, from biological to mechanical, all combining to produce a specific message to the cell. Moreover, human environment is intrinsically fluidic, specifically fluid-dynamic. With MIVO technology, a new era in the 3D fluido-dynamic human tissue culture can start.
MIVO® is the first product of React4life for in vitro testing. It is a technology combining 3D human tissue and fluidic system to mimic physiological organ with the highest reliability. Thanks to this technology, React4life help scientific community to:
- Drastically reduce animal experiments
- Reduce R&D testing costs, since promising drugs are identified earlier
- Make easier and faster the testing assays, since MIVO® is storable, ready-to-use and flexible
React4life team is hardly working to new approaches for the cancer treatment research. Thanks to our international partners, MIVO® product has been already adopted for drug efficacy test against ovarian cancer, and for immuno-therapies testing against neuroblastoma paediatric cancer.