MIVO CHIPS

CANCER-on-CHIP

An advanced platform for studying the complex interactions between cancer cells and their microenvironment

A more accurate and efficient approach for studying the mechanisms behind cancer growth and progression. This cutting-edge technology provides a potent platform for investigating the complex interactions between cancer cells and their microenvironment in a controlled environment.

With our innovative Cancer-on-Chip precision and accuracy are improved, leading to accelerated drug discovery timelines and improved outcomes.

Tissue Models Options
CANCER-ON-CHIP
Monolayer231

2D cells monolayers

Histology

Matrix based tumor models

Spheroids, Organoids, Biopsies

Patient derived biopsy

Patient derived Biopsies

APPLICATIONS

Recapitulate tumor microenvironment and circulating tumor cells dynamic

Drug Screening

Test the efficacy and safety of new cancer drugs and combinations in a more predictable microenvironment

Personalized medicine

Develop personalized cancer treatments by using patient-derived tumor cells to evaluate therapies response and evaluate the most appropriate

Cancer cell migration and invasion

Study the mechanisms underlying cancer cell migration and invasion, with the aim of identifying new therapeutic targets for preventing metastasis

Tumor to metastatic target 

Study the mechanisms underlying cancer metastasis and identify new therapies by connecting primary tumor with the target tissue

Tumor microenvironment

Explore the complex interactions between cancer cells, immune cells, and stromal cells in the tumor microenvironment

Rare cancers

Develop models of rare and hard-to-study cancers providing a valuable platform for research and drug development

POSSIBLE OUTCOMES

Cancer-on-Chip Model

A more realistic and physiologically relevant environment for more predictive readouts

Cells Intravasation

CANCER CELLS EXTRAVASATION

Measuring cancer cells intravasation in a humanized platform provides valuable readout for evaluating the effectiveness of anti-metastatic therapies and identifying key molecular pathways involved in this process.

Cell viability

Cell Viability

After the permeation of testing compounds, cell viability is evaluated through a live/dead assay to detect the optimal dose and evaluate the potential cytotoxic effect

Molecular Analysis

Omics studies

Providing valuable insights into disease pathways, identifying new drug targets, and developing personalized medicine approaches, while offering an effective means of characterizing the cellular and molecular effects of novel compounds or treatments.

PHENOTYPE CHARACTERIZATION

PHENOTYPE CHARACTERIZATION

A phenotype characterization of cancer cells can be performed by flow cytometry, to identify different resident or circulating subpopulations

DRUG EFFICACY

DRUG EFFICACY

Evaluating efficacy of chemotherapic compounds in a more reliable and predictive environment, allowing a more efficient drug diffusion

Immuno Oncology IMMUNE CELLS INFILTRATION

IMMUNE CELLS INFILTRATION

Immune cells infiltration is assessed by immunofluorescence and/or confocal microscopy.

Publications

Find a selection of publications for research purposes.

Publications

Workshops

Find a selection of posters for research purposes.

Workshops

Webinars

Find a selection of protocols for research purposes.

Webinars
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